Abeomics/Paritaprevir/5 mg/15-4006,Abeomics,,Abeomics,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Abeomics/Paritaprevir/5 mg/15-4006

产品编号：15-4006

市场价：¥5000.00

场地：美国(厂家直采)

产品分类：分子类>其他分子产品>酶抑制剂>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$250.00

品牌： Abeomics

公司：Abeomics

公司分类：

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Amount :	10 mg
Purification :	≥98%
Content :	Paritaprevir is supplied as a solid.
Storage condition :	Store at -20°C, product is stable for at least two years.


Alternative Name :	ABT-450

Molecular Formula:C₄₀H₄₃N₇O₇S

Molecular Weight:765.9

Paritaprevir is an orally bioavailable, direct-acting inhibitor of the hepatitis C virus (HCV) non-structural 3/4A (NS3/4A) serine protease.It inhibits HCV replication in stable Huh7-derived replicon cell lines infected with subgenomic genotypes 1a, 1b, 2a, 3a, 4a, and 6a (EC50s = 1, 0.21, 5.3, 19, 0.09, and 0.69 nM, respectively). It also inhibits replicons from clinical isolates of genotypes 1a (EC50s = 0.43-1.87 nM) and 1b (EC50s = 0.033-0.087 nM). Formulations containing paritaprevir in combination with ombitasvir, ritonavir, and dasabuvir with and without ribavirin have been used in the treatment of chronic HCV genotype 1 infection.

A stock solution may be made by dissolving the paritaprevir in the solvent of choice, which should be purged with an inert gas. Paritaprevir is soluble in organic solvents such as DMSO and dimethyl formamide. The solubility of paritaprevir in these solvents is approximately 30 mg/ml.

Paritaprevir is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, paritaprevir should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Paritaprevir has a solubility of approximately 0.17 mg/ml in a 1:5 solution of DMSO:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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品牌介绍

Abeomics Inc.致力于帮助科学家摆脱常规的动手实验室工作，从而帮助他们开展更多的创造性研究。我们通过提供定制和合同实验室服务来做到这一点，以缩短您的研发时间，并使您更快地专注于后续步骤。Abeomics由一组经验丰富的科学家组成，他们还建立了成功的全球业务，其中包括世界一流的生命科学试剂和合同实验室服务提供商IMGENEX Inc.，以及用于系统生物学和临床医学的复杂的交互式Web数据库Protein Lounge。生物信息学。

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